Ascend Research
GH-Axis Receptor

Ipamorelin5mg–10mg

$65

Lyophilized Ipamorelin supplied as a research reference standard.

Size: 5mg
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For in vitro laboratory research use only. Not for human consumption. Not for human or veterinary use. Not for diagnostic or therapeutic use.

Supplied to qualified labs and institutional buyers. Institutional use & eligibility

Frequently researched together

GLP-3 RT

GLP-3 RT

20mg

$150

KLOW

KLOW

80mg

$195

CJC-1295 + Ipamorelin

CJC-1295 + Ipamorelin

10mg + 10mg

$190

Bundle total

$535

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Characteristics

Characteristics of Ipamorelin
Molecular FormulaC₃₈H₄₉N₉O₅
CAS Number170851-70-4
Molar Mass711.85 g/mol
Amino Acid SequenceAib-His-D-2-Nal-D-Phe-Lys-NH₂ (pentapeptide)
SynonymsNNC 26-0161, Ipamorelin acetate
Physical FormLyophilized powder
SolubilitySoluble in water and aqueous laboratory solvent
Organoleptic ProfileWhite lyophilized powder; odorless
Storage ConditionsStore lyophilized at -20°C; reconstituted solution stable at 2-8°C for up to 21 days
CompositionLyophilized ipamorelin acetate salt

How is Ipamorelin used in research?

Ipamorelin is a 5-amino acid synthetic pentapeptide growth hormone secretagogue supplied as a lyophilized reference standard for in-vitro GHS-R1a (ghrelin receptor) binding assays and selectivity profiling. The compound is characterized in laboratory workflows as a high-selectivity GHS-R1a ligand; in-vitro binding assays profile its affinity relative to broader-spectrum GHS reference compounds such as GHRP-6 and GHRP-2.

At the molecular level, ipamorelin is studied in recombinant GHS-R1a expression systems and cultured pituitary somatotroph cell lines. Binding activates phospholipase C through Gq/11-protein coupling; standard laboratory readouts include IP1/IP3 accumulation assays and intracellular calcium-flux assays. The pentapeptide's selectivity is profiled in parallel panels against cortisol, ACTH, prolactin, FSH, LH, and TSH receptor systems - making it a useful reference tool for receptor-selectivity characterization.

Researchers use ipamorelin as a reference standard in analytical method development (HPLC identity and purity assays, LC-MS mass-accuracy work) and as a GHS-R1a reference ligand for comparability testing of novel secretagogue analogs. Not for use in any living organism.

Areas of Study

In-Vitro GHS-R1a Binding Assays

Applied as a reference ligand in competitive binding and functional (IP1, calcium-flux) assays on recombinant GHS-R1a cell systems.

Receptor Selectivity Profiling

Used in multi-receptor panels to characterize selectivity versus cortisol, ACTH, prolactin, FSH, LH, and TSH receptor systems.

Analytical Method Development

Serves as an identity and purity reference standard in HPLC, LC-MS, and comparability work against novel GHS analogs.

Structural Characterization

Characterized by mass spectrometry and circular dichroism to confirm sequence identity and secondary-structure content of the pentapeptide.

Combination Receptor Studies

Used alongside GHRH-receptor reference ligands such as CJC-1295 no DAC in two-receptor in-vitro co-activation studies.

References

  1. [1]Raun K, Hansen BS, Johansen NL, et al. (1998). Ipamorelin, the first selective growth hormone secretagogue. European Journal of Endocrinology, 139(5), 552-561.
  2. [2]Johansen PB, Nowak J, Skjaerbaek C, et al. (1999). Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats. Growth Hormone & IGF Research, 9(2), 106-113.
  3. [3]Anderson LL, Jeftinija S, Scanes CG, et al. (2004). Physiology of ghrelin and related peptides. Domestic Animal Endocrinology, 29(1), 111-144.

Disclaimer: Information provided for research reference only; not medical advice. Sold strictly for in-vitro research use.

Certificate of Analysis

Third-party verified

Every batch of Ipamorelin is independently tested by an A2LA-accredited (ISO 17025:2017) laboratory using HPLC-UV/VIS for purity and identity, with a batch-specific lot number. Results are published publicly.

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Frequently Asked Questions

Everything on purity, paperwork, shipping and the research-use-only terms. Still stuck? Read the full FAQ.

What does research use only mean?

Every compound we supply is an analytical-grade biochemical reference standard intended strictly for in vitro laboratory research. These products are not for human consumption. They are not a drug, food, supplement, or medical device, have not been evaluated by the U.S. Food and Drug Administration, and are not for human or veterinary use, diagnostic use, or therapeutic use.

Who do you supply?

We supply qualified researchers and institutional buyers: academic institutions, biotech companies, contract research organizations (CROs), and analytical laboratories. Purchasers must be at least 21 years of age and confirm that material is for in vitro laboratory research only.

How is purity verified?

Every lot is assayed by HPLC at an independent, accredited third-party laboratory. We publish the resulting Certificate of Analysis and link it to the lot number printed on the vial.

Where do I find the Certificate of Analysis?

Every lot has a public, batch-linked COA. Browse them all on the COA page, or open any product page and use the COA tab for that specific compound.

How quickly do orders ship?

Orders placed before 2PM EST ship the same business day. Shipments are cold-packed where required and fully tracked.

Do you ship internationally?

We currently ship within the United States. Requests from institutional buyers outside the US are handled case by case, so contact us before ordering.

99%+ purityCOA per lotSame-day ship

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